Opening Keynote: Jon McNeill and John Halamka, MD, MS

Part 1: Mastering Both Innovation and Scaling: Discover the Proven Algorithm for Success

As long as business has existed, people have been trying to find the secret to success, often unsuccessfully. But what if there really was a proven blueprint for growth? According to former Tesla president and Lyft COO Jon McNeill, the “algorithm for success” that’s been employed at Tesla and SpaceX has consistently delivered transformative results. In this fascinating presentation, McNeill – who led Tesla through a period of explosive growth, shares insights from his experiences and offers a deep dive into a proven method for accelerating innovation and scaling success. Through real-world examples, he unpacks the key steps of “the algorithm,” why it works, and how organizations, across industries, have leveraged it. Attendees will walk away with a practical, actionable framework they can apply immediately within their organization to drive growth and turn bold ideas into reality. 

Part 2: Driving the Future of Health with Platform Innovation

In Part 2 of this keynote experience, John Halamka, M.D., M.S., the Dwight and Dian Diercks President of Mayo Clinic Platform, will continue the conversation on driving and scaling healthcare innovation. Building on the concepts introduced in Part 1 of this keynote, he will discuss how collaboration within the Mayo Clinic Platform ecosystem advances innovation, data-powered insights and scalable AI solutions. Further, he will highlight the impact of Platform’s portfolio of AI-powered tools and next-generation care models at Mayo Clinic and beyond, drawing parallels to scaling breakthroughs in other industries. Attendees will leave the HIMSS26 opening keynote energized and equipped with practical strategies to lead meaningful transformation across healthcare.